Semaglutide is a drug that acts as a glucagon-like peptide-1 receptor agonist. It is used to treat type 2 diabetes and obesity.
Semaglutide reduces total body weight and fat mass by decreasing energy intake.
This mechanism involves a general reduction in appetite, including increased satiety signals and decreased hunger signals, as well as improved control of food intake and reduced food cravings. Insulin resistance is also reduced, possibly due to weight loss. In addition, Semaglutide reduces the preference for foods high in fat. By acting on isolated areas of brain tissue, Semaglutide activates neurons associated with satiety and suppresses neurons associated with hunger.
